{"id":1467,"date":"2022-07-24T09:52:48","date_gmt":"2022-07-24T12:52:48","guid":{"rendered":"https:\/\/ingenieriabiologicaymedica.uc.cl\/?p=1467"},"modified":"2025-02-04T09:56:03","modified_gmt":"2025-02-04T12:56:03","slug":"cientifico-del-instituto-de-ingenieria-biologica-y-medica-esta-entre-los-becarios-de-pew-charitable-truts","status":"publish","type":"post","link":"https:\/\/ingenieriabiologicaymedica.uc.cl\/en\/cientifico-del-instituto-de-ingenieria-biologica-y-medica-esta-entre-los-becarios-de-pew-charitable-truts\/","title":{"rendered":"Cient\u00edfico del Instituto de Ingenier\u00eda Biol\u00f3gica y M\u00e9dica est\u00e1 entre los becarios de Pew Charitable Truts"},"content":{"rendered":"
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En el laboratorio de Julius Lucks, son expertos en estudiar las din\u00e1micas estructurales de las mol\u00e9culas de ARN. Aprender de sus t\u00e9cnicas, ser\u00e1 clave para analizar la interacci\u00f3n entre los riboswitches y nuevas clases de antibi\u00f3ticos.<\/strong><\/p>\n

El 14 de junio, Pew Charitable Truts dio a conocer a los miembros de la clase 2022 del Programa Pew Latin American Fellows en Ciencias Biom\u00e9dicas y el Bioqu\u00edmico de la Pontificia Universidad Cat\u00f3lica de Chile,\u00a0An\u00edbal Arcelaunch<\/i><\/a>, es uno de los 10 becarios posdoctorales seleccionados entre cinco pa\u00edses de Latinoam\u00e9rica (Chile, M\u00e9xico, Argentina, Colombia y Brasil).<\/p>\n

Para el cient\u00edfico de 32 a\u00f1os\u00a0\u201cel apoyo que da Pew es gigantesco, es una beca de muy alto impacto a nivel latinoamericano. Pew financia a cient\u00edficos j\u00f3venes para formarse en Estados Unidos durante unos a\u00f1os, y luego, los ayuda a volver para instalarse en la academia; as\u00ed, varios cient\u00edficos de Chile y de la regi\u00f3n han sido becarios Pew\u201d.<\/em><\/p>\n

An\u00edbal comenta que tan solo el hecho de postular a la beca es muy enriquecedor\u00a0\u201cuno se enfrenta al problema de pensar un proyecto que sea apasionante y novedoso; pulir las ideas en conjunto con un tutor en USA; y defender el proyecto frente a comisiones evaluadoras a medida que se avanza en las etapas. Todo el proceso de postulaci\u00f3n abre muchas oportunidades de interacci\u00f3n con otros cient\u00edficos, ex becarios y profesores, lo cual es muy valioso. Ojal\u00e1 que mi experiencia sirva de inspiraci\u00f3n y m\u00e1s gente se anime a postular en los pr\u00f3ximos llamados.\u201d<\/em><\/p>\n

Pew Charitable Truts entrega dos a\u00f1os de financiamiento para que los becarios puedan realizar investigaciones en laboratorios de Estados Unidos, con la tutor\u00eda de destacados cient\u00edficos biom\u00e9dicos.<\/p>\n

Entre los temas de investigaci\u00f3n a explorar por los becarios 2022, est\u00e1 c\u00f3mo las bacterias desarrollan resistencia a los antibi\u00f3ticos dirigidos al ARN, c\u00f3mo ciertas reacciones qu\u00edmicas ayudan a los beb\u00e9s a reconocer a sus madres y c\u00f3mo los cambios en el mantenimiento del ADN pueden provocar leucemia mieloide aguda.<\/p>\n

En particular, An\u00edbal Arce comenta que\u00a0\u201cnuestro proyecto busca entender unas mol\u00e9culas de ARN, muy interesantes que son los \u201criboswitches\u201d. Estos son sensores de mol\u00e9culas espec\u00edficas y pueden estructurarse din\u00e1micamente para modificar la expresi\u00f3n g\u00e9nica luego de la interacci\u00f3n con su ligando\u201d.<\/em><\/p>\n

\u201cAlgunos de estos riboswitches controlan factores de virulencia o genes esenciales en organismos pat\u00f3genos multiresistentes, por lo que son candidatos para el dise\u00f1o de nuevos tipos de antibi\u00f3ticos\u201d,<\/em>\u00a0puntualiz\u00f3.<\/p>\n

En el laboratorio de Julius Lucks, que recibe al cient\u00edfico chileno, son expertos en estudiar las din\u00e1micas estructurales de las mol\u00e9culas de ARN, por lo que utilizar las t\u00e9cnicas que han desarrollado, ser\u00e1 clave para analizar esos riboswitches.<\/p>\n

El Bioqu\u00edmico del Instituto de Ingenier\u00eda Biol\u00f3gica y M\u00e9dica de la Pontificia Universidad Cat\u00f3lica de Chile, An\u00edbal Arce, coment\u00f3 que el objetivo es\u00a0\u201cestudiar los mecanismos de resistencia que pueden emerger en los riboswitches de las bacterias pat\u00f3genas, para defenderse de estos antibi\u00f3ticos, y trabajar en la implementaci\u00f3n de una plataforma para la evaluaci\u00f3n r\u00e1pida de nuevas mol\u00e9culas que puedan interrumpir la funci\u00f3n de estos riboswitches. De esta manera esperamos contribuir tanto al conocimiento fundamental de los riboswitches, como a la b\u00fasqueda de nuevos agentes antimicrobianos\u201d.<\/em><\/p>\n

M\u00e1s informaci\u00f3n aqu\u00edlaunch<\/i><\/a><\/p>\n<\/div>\n<\/div><\/div><\/div><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"

En el laboratorio de Julius Lucks, son expertos en estudiar las din\u00e1micas estructurales de las mol\u00e9culas de ARN. Aprender de sus t\u00e9cnicas, ser\u00e1 clave para analizar la interacci\u00f3n entre los riboswitches y nuevas clases de antibi\u00f3ticos. El 14 de junio, Pew Charitable Truts dio a conocer a los miembros de la clase 2022 del Programa […]<\/p>\n","protected":false},"author":1,"featured_media":1468,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[46],"tags":[],"class_list":["post-1467","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-noticias"],"yoast_head":"\nCient\u00edfico del Instituto de Ingenier\u00eda Biol\u00f3gica y M\u00e9dica est\u00e1 entre los becarios de Pew Charitable Truts - Institute for Biological and Medical Engineering<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ingenieriabiologicaymedica.uc.cl\/cientifico-del-instituto-de-ingenieria-biologica-y-medica-esta-entre-los-becarios-de-pew-charitable-truts\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Cient\u00edfico del Instituto de Ingenier\u00eda Biol\u00f3gica y M\u00e9dica est\u00e1 entre los becarios de Pew Charitable Truts - Institute for Biological and Medical Engineering\" \/>\n<meta property=\"og:description\" content=\"En el laboratorio de Julius Lucks, son expertos en estudiar las din\u00e1micas estructurales de las mol\u00e9culas de ARN. 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