Quantitative Physiology

Quantitative Physiology aims to understand the normal functions of living organisms and their parts from a quantitative perspective using an engineering approach based on mathematical models and analysis. Quantitative Physiology scope ranges from the molecular processes that are the foundation of how living cells function in a physiological context to major physiological systems of the human body, e.g., cardiovascular, endocrine, digestive, and immune system.

Research in our Institue aims to understand complex biological systems by integrating high-throughput experimental techniques, data processing, and computational models. One of the main axes is devoted to the development of new algorithms to improve several steps of the model building process, namely, parameter estimation, sensitivity analysis, and optimal experimental design. Another key area is focused on the development of mechanistic and physiologically based computational models that can aid the identification of the molecular pathways underlying different biological and clinical problems